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4egi1 α  (MedChemExpress)


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    Structured Review

    MedChemExpress 4egi1 α
    4egi1 α, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 26 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/4egi1+%CE%B1/4EGI-1/pmc11332907-188-0-22
    Average 94 stars, based on 26 article reviews
    4egi1 α - by Bioz Stars, 2026-09
    94/100 stars

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    other:

    Article Title: MGST3 regulates BACE1 protein translation and amyloidogenesis by controlling the RGS4-mediated AKT signaling pathway.
    Article Snippet: Microsomal glutathione transferase 3 (MGST3) regulates eicosanoid and glutathione metabolism.. These processes are associated with oxidative stress and apoptosis, suggesting that MGST3 might play a role in the pathophysiology of Alzheimer's disease (AD).. Here, we report that knockdown (KD) of MGST3 in cell lines reduced the protein level of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) and the resulting amyloidogenesis.

    Article Title: MGST3 regulates BACE1 protein translation and amyloidogenesis by controlling the RGS4-mediated AKT signaling pathway
    Article Snippet: 4EGI1 (α-[2-[4-(3,4-Dichlorophenyl)-2-thiazolyl] hydrazinylidene] -2-nitro-benzenepropanoic acid), BAY u9773 [6(R)-(4′-carboxyphenylthio)-5(S)-hydroxy-7(E), 9(E), 11(Z),14(Z)-eicosatetraenoic acid], Baf A1, γ-secretase inhibitor (DAPT), CCG-50014, and LY294002 were purchased from MedChemExpress (Monmouth Junction, Cat#HY-19831, Cat#HY-107069, Cat#HY-100558, Cat#HY-13027, Cat#HY-13509, Cat#HY-10108).



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    94
    MedChemExpress 4egi1 α
    4egi1 α, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/4egi1+%CE%B1/4EGI-1/pmc11332907-188-0-22
    Average 94 stars, based on 1 article reviews
    4egi1 α - by Bioz Stars, 2026-09
    94/100 stars
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